Skip to main content
. 2019 May 9;62(12):5863–5884. doi: 10.1021/acs.jmedchem.9b00335

Scheme 12. Synthetic Routes to Amide Analogues 4d and 5e.

Scheme 12

Reagents and conditions: (a) 1 M NaOH, MeOH, rt; (b) (COCl)2, DMF, DCM, rt; (c) benzylamine, DCM, rt; (d) H2, Pd/C, THF, rt.