Table 2.

Patients with recurrent disease.

Patient number	Site of recurrence	Time of recurrence following primary nephrectomy (months)	Timing of secondary surgical resection after diagnosis of recurrence (months)	Resection margins	Therapeutic details	Outcome
2	Local	5	4	Microscopic positive	VA, 4 cycles then resection, 6 cycles cyclophosphamide and doxorubicin	Alive and well, disease free
5	Lung	2	5	Negative	2 cycles VAC, then 6 cycles VDC due to disease progression then resection. Lung irradiation	Died from acute on chronic respiratory failure
6	Local	2	No surgery	N/A	2 cycles of neoadjuvant VA, then surgery because of progression. 12 months of individualised treatment after recurrence with cyclophosphamide, doxorubicin, carboplatin and etoposide	Alive and well, disease free

VA, vincristine and actinomycin; VAC, vincristine, adriamycin and cyclophosphamide; VDC, vincristine, doxorubicin, cyclophosphamide.