Fig. 5.

HHcy redistributes amyloid to the vasculature at 14 weeks on diet in the APP/PS1 mice despite no effect of HHcy on total Abeta levels. a–f Representative images of Congo red staining in the frontal cortex of APP/PS1 mice on control diet or HHcy diet for 10, 14, or 18 weeks are shown. Magnification = × 200X. Scale bar in A = 50 μm for all images. Black arrows indicate amyloid around a vessel. g-h Quantification of percent positive stain in the frontal cortex (g) and hippocampus (h). * indicates P < 0.05, ** indicates P < 0.01 compared to APP/PS1 mice on control diet at that time point