Table 2.

Overview of study procedures

Procedure	Screening	Baseline cognitive testing		Month 3	Month 6	Month 9	End-of-study cognitive testing
		Scopolamine challenged	Non-challenged				Scopolamine challenged	Non-challenged
Study week	−5 ± 2 weeks	− 4 ± 1	0 ± 1	13 ± 1	26 ± 1	39 ± 1	52 ± 1	56 ± 1
Demographics	X
Health history	X	X	X	X	X	X	X	X
Medication review	X	X	X	X	X	X	X	X
NAART	X
TMTB		X	X				X	X
CVLT		X	X				X	X
MoCA		X	X				X	X
SF-36	X							X
ECG	X
Physical exam	X							X
Neurological exam	X							X
Gait and balance	X	X			X		X	X
Aβ-PET imaging	X
MTM intervention			X		X		X
Telephone follow-up				X		X

NAART North American Adult Reading Test, TMTB Trail Making Test B, CVLT California Verbal Learning Test, MoCA Montreal Cognitive Assessment, SF-36 Short-Form 36, ECG electrocardiogram, Aβ amyloid beta, PET positron emission tomography, MTM medication therapy management