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. 2019 Dec 30;20:816. doi: 10.1186/s13063-019-3946-7

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Standard protocol items (SPIRIT): schedule for data collection. ¹Blood tests to be performed include blood counts, total bilirubin, albumin, alanine aminotransferase, aspartate aminotransferase, γ-glutamyl transpeptidase, alkaline phosphatase, amylase, blood urea nitrogen, creatinine, and C-reactive protein. ²Electrocardiography and thoraco-abdominal radiography will be performed for safety evaluation during the pre-treatment observation period. ³Adverse events monitored will include all unfavorable events, including adverse reactions not related to the EUS-FNA procedure. EUS-FNA endoscopic ultrasound-guided fine-needle aspiration