Fig. 1.

Relative abundance (%) of dominant (a) and minor/rare (b) phylum-specific 16S rRNA gene amplicon sequences in human faecal samples collected from patients with primary progressive multiple sclerosis (2) and from healthy subjects (1). The marker shows a median; the box shows the 75–25% quartile range, while the lines indicate the fluctuation range. The p-values of the Mann-Whitney test for the cohorts’ comparison are shown in brackets after the phylum name