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. Author manuscript; available in PMC: 2020 Aug 1.
Published in final edited form as: Adv Drug Deliv Rev. 2019 Feb 12;148:344–359. doi: 10.1016/j.addr.2019.01.011

Fig. 4.

Fig. 4.

Influence of PEGylation on liposome circulation in vivo in zebrafish. A) Liposome formulations (DSPC/cholesterol with increasing amounts of DSPE-PEG2000) were injected into transgenic zebrafish embryos and images were taken at 1 and 24 h post-injection. B) The circulation factor (CF) and extravasation factor (EF) of each lipid composition were calculated. n ≥ 5 experiments. Box plots represent median, third and first quantiles, minima and maxima. *p > 0.05 as compared to control (0 mol% PEG). Reproduced by permission of Journal of Controlled Release [60].