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. 2019 Dec 30;19:1257. doi: 10.1186/s12885-019-6490-7

Table 1.

Minor allele frequencies of gene polymorphisms in breast cancer patients and healthy controls

Gene SNP ID Cases (n = 218) Controls (n = 219)
MAa MAFb HWEc
p-value
MAa MAFb HWEc
p-value
ESR1 rs3020410 A 0.1 0.44 A 0.08 0.63
rs3798577 C 0.41 0.33 C 0.48 0.68
rs2234693 T 0.49 0.34 T 0.49 0.03
rs9340799 G 0.47 0.5 G 0.46 0.02
ESR2 rs1256049 T 0.02 1 T 0.02 1
HER2 rs1058808 C 0.32 0.76 C 0.32 0.21
UGT1A4 rs12468274 C 0.08 0.37 C 0.07 0.61
rs2011425 G 0.09 0.23 G 0.09 0.38
rs6755571 A 0.06 0.54 A 0.05 0.11
UGT2B7 rs28365062 G 0.16 0.2 G 0.17 0.47
rs4348159 T 0.16 0.13 T 0.17 0.13

aMA: minor allele. bMAF: minor allele frequency. cHWE: Hardy—Weinberg equilibrium. N/A not applicable