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. 2019 Dec 30;12:145. doi: 10.1186/s13045-019-0835-1

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Overall survival by prognostic score. The five risk factors correlating independently with shorter survival were non-matched therapy (1 point), performance status > 1 (2 points), liver metastases (1 point), LDH levels > upper limit of normal (1 point), and PI3K/Akt/mTOR pathway alterations (1 point)