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. 2019 Dec 30;12:201. doi: 10.1186/s12920-019-0649-6

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — The effect of miR-361-5p on MEG3 in OA chondrocytes. a, qRT-PCR detection of miR-361-5p expression. b, cell proliferation detected by CCK-8 assay. c, detection of PCNA, Ki67 expression by western blot. d, flow cytometry was used to detect the apoptosis of OA chondrocytes in each group. e, the expression of apoptotic proteins Bcl-2 and Bax detected by Western Blot. f, Western blot analysis of cartilage matrix protein expression in chondrocytes of each group. *, P < 0.05 compared with Blank group or NC + mimics NC group. ^#, P < 0.05 compared with MEG3 + mimics NC group