Table 7.
Subanalysis for results of mixed-effects regression models predicting cognitive test performance from dietary cholesterol and egg intake by different educational groups
| Cognitive tests | Dietary cholesterol2 | Dietary cholesterol | Egg intake2 | Egg intake | ||||
|---|---|---|---|---|---|---|---|---|
| β | P value | β | P value | β | P value | β | P value | |
| Elementary school (n = 418) | ||||||||
| MoCA | 0.00000347 | 0.257 | −0.004239 | 0.102 | 0.0000902 | 0.202 | −0.020563 | 0.048* |
| AVLT-IR | −0.00000105 | 0.746 | −0.001233 | 0.654 | 0.0000432 | 0.56 | −0.017803 | 0.107 |
| AVLT-SR | 0.00000115 | 0.501 | −0.002667 | 0.067 | 0.0000348 | 0.375 | −0.013017 | 0.026* |
| AVLT-LR | 0.000000766 | 0.693 | −0.002141 | 0.193 | 0.0000178 | 0.689 | −0.011021 | 0.095 |
| SDMT | 0.00000511 | 0.519 | −0.001092 | 0.87 | 0.0001744 | 0.342 | −0.009431 | 0.726 |
| DSF | 0.000000705 | 0.537 | −0.000568 | 0.557 | 0.00000138 | 0.958 | −0.001005 | 0.796 |
| LMT | 0.00000044 | 0.933 | −0.002083 | 0.641 | 0.0000577 | 0.624 | −0.017358 | 0.328 |
| Junior middle school (n = 925) | ||||||||
| MoCA | −0.00000223 | 0.064 | 0.002945 | 0.011* | −0.0000345 | 0.167 | 0.0077031 | 0.087 |
| AVLT-IR | −0.00000349 | 0.062 | 0.004374 | 0.015* | −0.0000191 | 0.622 | 0.0079525 | 0.255 |
| AVLT-SR | −0.00000199 | 0.038* | 0.001977 | 0.032* | −0.0000191 | 0.336 | 0.0032397 | 0.366 |
| AVLT-LR | −0.00000158 | 0.136 | 0.001501 | 0.138 | −0.00000175 | 0.936 | 0.0001187 | 0.976 |
| SDMT | −0.0000127 | 0.002* | 0.010674 | 0.005* | −0.0001801 | 0.030* | 0.0240724 | 0.108 |
| DSF | −0.000000446 | 0.378 | 0.000669 | 0.167 | −0.000023 | 0.028* | 0.0051033 | 0.007* |
| LMT | −0.00000132 | 0.553 | 0.003593 | 0.091 | −0.0000423 | 0.357 | 0.013091 | 0.114 |
| Senior middle school (n = 764) | ||||||||
| MoCA | −0.00000155 | 0.075 | 0.002437 | 0.013* | −0.00000089 | 0.988 | 0.0045697 | 0.483 |
| AVLT-IR | −0.00000141 | 0.336 | 0.002893 | 0.078 | 0.0000611 | 0.521 | −0.001338 | 0.902 |
| AVLT-SR | −0.00000127 | 0.091 | 0.000801 | 0.342 | −0.00000153 | 0.975 | − 0.001089 | 0.845 |
| AVLT-LR | −0.00000132 | 0.112 | 0.000674 | 0.47 | −0.0000122 | 0.822 | 0.0005769 | 0.926 |
| SDMT | −0.0000018 | 0.606 | 0.002899 | 0.459 | 0.00000761 | 0.973 | 0.0012421 | 0.962 |
| DSF | −0.000000936 | 0.011* | 0.001025 | 0.013* | − 0.0000315 | 0.184 | 0.0068822 | 0.011* |
| LMT | −0.00000268 | 0.183 | 0.002725 | 0.226 | 0.0000091 | 0.944 | 0.0061439 | 0.679 |
| College and above (n = 407) | ||||||||
| MoCA | −0.0000011 | 0.511 | 0.001583 | 0.309 | −0.0001057 | 0.052 | 0.0134549 | 0.053 |
| AVLT-IR | −0.00000213 | 0.544 | 0.001039 | 0.75 | − 0.0002722 | 0.016* | 0.0243167 | 0.092 |
| AVLT-SR | 0.000000363 | 0.839 | 0.000177 | 0.915 | −0.0000809 | 0.16 | 0.0097477 | 0.186 |
| AVLT-LR | 0.000000472 | 0.811 | 0.000178 | 0.923 | −0.0000889 | 0.162 | 0.0101086 | 0.214 |
| SDMT | 0.00000371 | 0.662 | −0.005496 | 0.486 | − 0.0000766 | 0.778 | − 0.012119 | 0.728 |
| DSF | −0.000000251 | 0.782 | −0.000251 | 0.766 | −0.0000345 | 0.241 | 0.0033226 | 0.378 |
| LMT | 0.00000291 | 0.47 | −0.001744 | 0.639 | −0.0001277 | 0.332 | 0.0196316 | 0.242 |
Abbreviations: MoCA Montreal Cognitive Assessment, AVLT-IR auditory verbal learning test-immediate recall, AVLT-SR auditory verbal learning test-short recall, AVLT-LR auditory verbal learning test-long recall, SDMT symbol digit modalities test, DSF digit span forwards, LMT logical memory test
β: unstandardized regression coefficients were obtained from mixed-effects regression models adjusted for sex, age, BMI, smoking and drinking status, diabetes, hypertension and coronary artery disease history and per se use of lipid-lowering medication, number of APOE ε4 alleles and intakes of energy, protein, carbohydrates, fat, SFA, PUFA, and MUFA
Elementary school: ≤6 years of education; Junior middle school: 7–9 years of education; Senior middle school: 10–12 years of education; College and above: at least college or university; ≥13 years of education)
∗P < 0.05