Table 1.
Distribution of patient baseline characteristics
| Number | Percentage | |
|---|---|---|
| Age group | ||
| < 40 | 75 | 4.0 |
| 40–49 | 570 | 30.4 |
| 50–59 | 540 | 28.8 |
| 60+ | 687 | 36.7 |
| Median age (IQR) | 54 (47–64) | |
| Menopausal status | ||
| Pre-menopausal | 788 | 42.1 |
| Post-menopausal | 1084 | 57.9 |
| pN | ||
| pN0 | 1103 | 58.9 |
| pN1 | 449 | 24.0 |
| pN2 | 131 | 7.0 |
| pN3 | 189 | 10.1 |
| pT | ||
| pT1 | 1060 | 56.6 |
| pT2 | 612 | 32.7 |
| pT3/4 | 200 | 10.7 |
| Tumor grade | ||
| G1 | 279 | 14.9 |
| G2 | 1232 | 65.8 |
| G3 | 209 | 11.2 |
| Unknown | 152 | 8.1 |
| Vessel invasion | ||
| No | 1797 | 96.0 |
| Yes | 75 | 4.0 |
| Local treatment | ||
| Mastectomy w/o RT | 355 | 19.0 |
| Mastectomy w RT | 245 | 13.1 |
| Quadrantectomy w/o RT | 36 | 1.9 |
| Quadrantectomy w RT | 1236 | 66.0 |
| Adjuvant treatment | ||
| ET | 1481 | 79.1 |
| CT+ET | 391 | 20.9 |
| Hormonal therapy | ||
| Pre-menopausal | ||
| TAM | 107 | 13.6 |
| TAM+LHRH | 556 | 70.5 |
| AI+LHRH | 58 | 7.4 |
| Other | 67 | 8.5 |
| Post-menopausal | ||
| TAM | 483 | 44.6 |
| AI | 463 | 42.7 |
| Other | 138 | 12.7 |
| Receptor status | ||
| Incompletely expressed (ER < 50 or PgR < 50) | 841 | 44.9 |
| Highly expressed (ER ≥ 50 and PgR ≥ 50) | 1031 | 55.1 |
| Ki-67 | ||
| < 20% | 1375 | 73.5 |
| ≥ 20% | 497 | 26.5 |
| HER2 | ||
| Not expressed | 1727 | 92.3 |
| Intense and complete | 72 | 3.8 |
| Unknown | 73 | 3.9 |
| ER mean (SD)/median (IQR) | 83 (17)/90 (80–95) | |
| PgR mean(SD)/median (IQR) | 51 (37)/60 (10–90) | |
| Ki-67 mean(SD)/median (IQR) | 15 (9)/14 (9–20) | |