Table 1.
Quality Assesment | ||||||||
---|---|---|---|---|---|---|---|---|
RCT study | Author | Prospective design | Clear definition of study population | (1) | (2) | (3) | (4) | (5) |
Abraldes, et al. 2009 [21] | Yes | Yes | Yes | Stable | Yes | Yes | Yes | |
Pollo-Flores, et al. 2015 [32] | Yes | Yes | Yes | Stable | Yes | Yes | Yes | |
Abraldes, et al. 2016 [22] | Yes | Yes | Yes | Stable | Yes | Yes | Yes | |
Bishnu, et al. 2018 [24] | Yes | Yes | Yes | Stable | Yes | Yes | Yes | |
Elwan, et al. 2018 [26] | Yes | Yes | Yes | Stable | Yes | Yes | Yes | |
Domenico, et al | Yes | Yes | Yes | Stable | Yes | Yes | Yes | |
non-RCT study | Author | Study design | Clear definition of study population | Clear definition of different type of statin | Clear definition of related endpoints | Blindness to a statin or placebo |
Representativeness of the study population |
Comparability between case and control groups |
Kumar, et al. 2014 [30] | Propensity Score Matching Case-control Study | Yes | Yes | Yes | No | Yes | Yes | |
Simon, et al. 2015 [34] | Cohort study | Yes | No | Yes | Not given | Yes | Yes | |
Yang, et al. 2015 [37] | Propensity Score Matching Case-control Study | Yes | No | Yes | No | Yes | Yes | |
Huang, et al. 2017 [27] | Propensity Score Matching Case-control Study | Yes | No | Yes | No | Yes | Yes | |
Mohanty, et al. 2016 [31] | Propensity Score Matching Case-control Study | Yes | Yes | Yes | Not given | Yes | Yes | |
Simon, et al. 2016 [33] | Case-control Study | Yes | Yes | Yes | No | Yes | Yes | |
Bang, et al. 2017 [23] | Case-control Study | Yes | No | Yes | No | Yes | Yes | |
Chang, et al. 2017 [25] | Propensity Score Matching Case-control Study | Yes | No | Yes | Not given | Yes | Yes | |
Kim, et al. 2017 [13] | Nested Case-control Study | Yes | Yes | Yes | No | Yes | Yes | |
Wong, et al. 2017 [36] | Propensity Score Matching Case-control Study | Yes | Yes | Yes | No | Yes | Yes | |
Wani, et al. 2017 [35] | Self-control Study (Prospective Cohort) | Yes | Yes | Yes | No | Yes | Yes | |
Kaplan, et al. 2019 [28] | Propensity Score Matching Case-control Study | Yes | No | Yes | Not given | Yes | Yes |
(1) whether the study design was suitable for the disease condition and statin treatment; (2) were statin treatment stable or fluctuating; (3) was different cohort comparable to each other; (4) was there any clear definition of end event; (5) was plan of follow-up clearly given