Table 2.
Demography of patients in included studies
| Author | Year | Age (year) | Male (%) | Number | Aetiology of liver disease | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Alcoholic | HBV | HCV | NAFLD | Others | |||||||||||||
| Control | Statin | Control | Statin | Control | Statin | Control | Statin | Control | Statin | Control | Statin | Control | Statin | Control | Statin | ||
| Abraldes, et al | 2009 | 56 ± 10 | 58 ± 10 | 21 | 17 | 27 | 28 | 12 | 11 | 2 | 0 | 13 | 4 | – | – | 0 | 3 |
| Kumar, et al | 2014 | 59.6 ± 10.6 | 59.8 ± 10.9 | 88 (54.32) | 44 (54.3) | 162 | 81 | 39 (24.1) | 18 (22.2) | 10 (6.2) | 2 (2.5) | 55 (34) | 18 (22.2) | 41 (25.3) | 35 (43.2) | 6 (3.7) | 3 (3.7) |
| Pollo-Flores, et al | 2015 | 58.5 ± 13.5 | 56.5 ± 8.7 | 50% | 57% | 20 | 14 | 4 | 3 | 5 | 4 | 7 | 9 | none | none | 1 | 1 |
| Simon, et al | 2015 | 50.1 ± 7.2 | 54.2 ± 7.2 | 71.2 | 58.6 | 514 | 29 | none | none | none | none | all | all | none | none | none | none |
| Yang, et al | 2015 | NG | NG | 23,602 (42) | 11,801 (42) | 56,142 | 28,071 | none | none | none | none | all | all | none | none | none | none |
| Mohanty, et al | 2016 | 54 (50–58) | 56 (52–60) | 671 (97.9) | 677 (98.8) | 685 | 685 | none | none | none | none | all | all | none | none | none | None |
| Huang, et al | 2016 | 49.7 ± 11.5 | 50 ± 11.1 | 3479 (53.2) | 3454 (52.8) | 6543 | 6543 | none | none | all | all | none | none | none | none | none | None |
| Simon, et al | 2016 | 52.5 ± 6.9 | 53.5 ± 5.9 | 95.37 | 96.16 | 4970 | 4165 | none | none | none | none | all | all | none | none | none | none |
| Abraldes, et al | 2016 | 57.6 ± 10.6 | 57.4 ± 11.3 | 53 (67.9) | 45 (65.2) | 78 | 69 | 55 (71.4) | 49 (71) | 2 (2.6) | 1 (1.4) | 17 (22.1) | 19 (27.5) | 4 (5.2) | 1 (1.4) | 11 | 6 |
| Wani, et al | 2017 | 58.5 ± 6 | 58.5 ± 6 | 21 | 21 | 38 | 38 | 12 | 12 | 15 | 15 | 15 | 15 | 11 | 11 | none | none |
| Wong, et al | 2017 | 59.9 ± 13.9 | 60 ± 13.1 | 21,835 (58.8) | 1266 (61.7) | 67,131 | 2053 | none | none | 61,692 (89.7) | 1867 (90.9) | 4925 (8.9) | 158 (7.7) | none | none | 514 (0.8) | 28 (1.4) |
| Bang, et al | 2017 | 54 ± 10 | 57 ± 9 | 60% | 61% | 496 | 248 | all | all | none | none | none | none | none | none | none | None |
| Chang, et al | 2017 | 57.5 ± 14.1 | 56.5 ± 11.2 | 476 (71) | 492 (73) | 675 | 675 | 231 (34) | 216 (32) | 292 (43) | 313 (46) | 152 (23) | 146 (22) | none | none | none | none |
| Kim, et al | 2017 | 61.8 ± 9.2 | 61.8 ± 9.2 | 6860 (83.6) | 1372 (83.6) | 8210 | 1642 | not given | |||||||||
| Bishnu, et al | 2018 | 46.7 (7.1) | 44 ± 12.7 | 12 (100) | 9 (81.2) | 12 | 11 | 6 (50) | 4 (36.4) | 1 (8.3) | 0 | 0 | 0 | 1 (8.33) | 0 | 1 (8.33) | 1 (9.09) |
| Kaplan, et al | 2019 | 63 (58–68) | 63 (58–67) | 98% | 98 | 12,860 | 6481 | 4876 (35.2) | 2334 (36) | none | none | 2065 (14.9) | 933 (14.4) | 2159 (15.6) | 1042 (16.1) | none | none |
| Elwan, et al. | 2019 | 50.8 ± 7 | 51.5 ± 6.7 | 16 (80) | 10 (50) | 20 | 20 | none | none | HCV 38, HBV 1, HCV + HBV 1 | none | none | none | ||||
SD Standard deviation, IQR Interquartile range, HBV Hepatitis B virus, HCV Hepatitis C virus, NAFLD Non-alcoholic fatty liver disease