. 2019 Dec 27;10:229–247. doi: 10.2147/VMRR.S201847

Table 3.

Overview Of MIC Distribution Of CA Mycoplasma Species (Microbroth Or Agar Dilution Methods Depending On The Study) And Main Molecular Resistance Mechanisms When Known

Mycoplasma Species	Fluoroquinolones		Phenicols		Tetracyclines		Macrolides		Lincosamides		Aminosides
	ENRO		FFC		OXY		TYL		LIN		SPT
	MIC Range MIC₉₀ Range µg/mL	Mec.	MIC Range MIC₉₀ Range µg/mL	Mec.	MIC Range MIC₉₀ Range µg/mL	Mec.	MIC Range MIC₉₀ Range µg/mL	Mec.	MIC Range MIC₉₀ Range µg/mL	Mec.	MIC Range MIC₉₀ Range µg/mL	Mec.
Ma ¹⁵²^,¹⁹⁶^,¹⁹⁸^,¹⁹⁹^,²⁰⁴^,¹⁹⁵	<0.125–0.8 0.1–0.5	Mutations in QRDR	1–8 2–8	ns	0.06–8 0.5–8	rrs mutations	0.025–16 0.25–8	rrn and L22 coding gene mutations	0.125–4 1–4	rrn and L22 coding gene mutations	0.4–12.8 2–8	ns
Mcc ²⁰⁰^,²⁰⁶^,²⁰⁷	0.025–3.2 0.25–0.4	Mutations in QRDR	4–8 8	ns	0.25–4 0.5–2	na	0.05–12.8 ≤0.03–12.8	rrn and L22 coding gene mutations	0.2–12.8 12.8	rrn and L22 coding gene mutations	16–128 128	ns
Mmc ¹⁹⁴^,¹⁹⁸^,²⁰⁰^,¹⁹⁷	0.025–0.2 0.1–0.125	na	2–4 4	ns	0.125–4 0.25–0.5	na	0.025–1 0.06–1	na	0.125–12.8 0.5–0.8	rrn and L22 coding gene mutations	8–128 16–64	ns
Mp ¹⁹³^,¹⁹⁸^,²⁰⁰	0.06–0.25 0.125–0.25	na	0.5–4 1	ns	0.250–8 0.5–4	na	0.015–2 0.015–0.12	na	0.250–16 1–2	rrn and L22 coding gene mutations	8–32 16–32	ns

Abbreviations: Mec., mechanism; ns, not studied so far; na, not applicable; ENRO, enrofloxacin; FFC, florfenicol; OXY, oxytetracycline, TYL, tylosin; LIN, lincomycin; SPT, spectinomycin.