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. 2018 Dec 18;69(8):1345–1352. doi: 10.1093/cid/ciy1066

Table 1.

Background and Clinical Characteristics

Variable 503 1018 3017 340 3025 3026 Escape (Median)a Suppressed (Median, Interquartile Range)
Gender Female Male Male Male Male Male
Race Black or African American Black or African American Black or African American American Indian/Alaska Native White White
T1 T2 T1 T2 T1 T2 T3
Age (years) 52 53 48 48 48 39 39 42 42 47 48 50 (42–56)
CSF VL (copies/mL) 117 89 47 209 54 1295 <40 265 356 <40 117 <40b
Plasma VL (copies/mL) <40 <40 <40 62 <40 <40 <40 <40 <40 <40 <40 <40b
CD4 (cells/mm3) 430 567 325 327 210 261 200 309 503 326 539 (389–693)b
Nadir CD4 (cells/mm3) 298 296 150 103 12 10 127 133 (34–253)c
CSF white blood cell count (cells/mm3) 3 134 1 1 87 4 2 1 2 2 1 (1–3)b
Months on ART 12 13 32 83 85 19 28 23 31 83 23 62 (19–123)d
ART regimen EFV, FTC, TDF EFV, FTC, TDF EFV, FTC, TDF DRV/r, TDF, FTC DRV/r, TDF, FTC DRV/r, TDF, FTC DRV/r, TDF, FTC DRV/r, TDF, FTC DRV/r, TDF, FTC BIC, FTC, TAF
ART regimen resistance mutations N/A N/A N/A N/A N/A None N/A M184V M184V N/A

Abbreviations: ART, antiretroviral therapy; BIC, bictegravir; CSF, cerebrospinal fluid; DRV/r, ritonavir-boosted darunavir; EFV, efavirenz; FTC, emtricitabine; N/A, not measured; T1, time point 1; T2, time point 2; T3, time point 3; TDF, tenofovir disoproxil fumarate; VL, viral load.

aFor participants with multiple escape time points, an average value was generated and used to calculate the median.

bA total of 95 participants.

cA total of 94 participants.

dA total of 92 participants.