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. 2019 Dec 27;12:11507–11516. doi: 10.2147/OTT.S222564

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© 2019 Liu et al.

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Overexpression of ARHGAP10 inhibited the proliferation and metastasis of CRC cells. (A, B). The proliferation rate was reduced in HT29 and RKO cells that transfected with oeARHGAP10. **p < 0.01 vs oeNC, ***p < 0.001 vs oeNC. (C, D). Overexpression of ARHGAP10 inhibited the migration and invasion of HT29 and RKO cells. ***p < 0.001 vs oeNC. (E, F). Western blot was used to examine the protein content of ARHGAP10, MMP2, MMP9, p-AKT and AKT in HT29 and RKO cells transfected with oeNC and oeARHGAP10, respectively, ***p < 0.001 vs oeNC.