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. 2020 Jan-Feb;25(1):75–77. doi: 10.5863/1551-6776-25.1.75

Table.

Epidiolex (Cannabidiol): Frequently Asked Questions for Patients and Caregivers

Question Response
What is Epidiolex? It is an FDA-approved, plant-derived, purified prescription cannabidiol, indicated for the treatment of seizures in patients 2 years and older.9
Is a state permit required for Epidiolex? No, it is an FDA-approved prescription medication (Schedule V), making it legal under federal law; therefore, no state permit is necessary.
Are cannabidiol and marijuana the same thing? No, CBD is derived from the cannabis (marijuana) plant; however, it is entirely different from marijuana and has none of the euphoric properties or abuse potential. CBD and THC are the 2 most frequent chemicals found in the plant.
Does Epidiolex contain THC? No. However, other CBD, “hemp,” and medical marijuana products available may contain small amounts of THC. These products are not regulated; therefore, there is variability in how much THC has been removed from these products and how much CBD is in these products.
Are Epidiolex and CBD the same thing? Epidiolex is the brand name for the pharmaceutical-grade cannabidiol oil product produced by Greenwich, whereas other CBD, “hemp,” and medical marijuana products available may contain small amounts of THC. These products are not regulated; hence, there is variability in how much THC has been removed from these products and how much CBD is in these products.
Is it possible to test positive for marijuana while on this drug? While on Epidiolex, patients may test positive on urine drug screenings. Patients/parents should inform the drug testing site that they are taking Epidiolex as prescribed by their doctor.
Will Epidiolex cause my child to have euphoria-like experiences (i.e., the “high”)? No, Epidiolex will not create euphoric effects because it does not contain any THC, which is the chemical compound in marijuana that creates the “high” effect.
Can my child become addicted to Epidiolex? No
How is Epidiolex formulated? Epidiolex comes in a strawberry-flavored, sesame oil–based oral solution.

CBD, cannabidiol; FDA, US Food and Drug Administration; THC, tetrahydrocannabinol