Table 2. Piecewise regression models assessing the relationships between X = FMRP level (normalized to normal controls) and Y = IQ, and estimated FMRP levels corresponding to IQ = 85 and 70.
IQ Measure | FMRP below -1SD | FMRP above -1SD | ||||||
---|---|---|---|---|---|---|---|---|
Fitted Regression Model | P-value | R2 value | Estimated FMRP levels | Fitted Regression Model | P-value | R2 value | ||
IQ = 70 | IQ = 85 | |||||||
Full Scale IQ | FSIQ = 54.48 + 88.97 FMRP | < 0.0001 | 0.481 | 0.174 | 0.343 | FSIQ = 111.24–2.78 FMRP | 0.6326 | 0.0021 |
Performance IQ | PIQ = 55.90 + 83.32 FMRP | < 0.0001 | 0.5063 | 0.169 | 0.349 | PIQ = 105.45–0.48 FMRP | 0.9274 | 0.0001 |
Verbal IQ | VIQ = 65.13 + 78.68 FMRP | <0.0001 | 0.3965 | 0.062 | 0.252 | VIQ = 116.72–3.36 FMRP | 0.5502 | 0.0033 |