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. 2019 Dec 31;14(12):e0226771. doi: 10.1371/journal.pone.0226771

Fig 5. CETP rs3764261 and nearby single nucleotide polymorphisms associated with lipid-related traits in a single Population Architecture using Genomics and Epidemiology (PAGE) study.

Fig 5

Plotted are single SNP tests of association in the Atherosclerosis Risk in Communities (ARIC) for CETP rs3764261 and nearby SNPs within 100kb of previously-reported genome-wide association study (GWAS) associations also associated here at p<1.0x10-4 with lipid-related traits. Data shown are sample size, coded allele frequency (CAF), genetic effect size (beta), -log10(p-value), and ARIC phenotypes on the y-axes. Each SNP is plotted on the x-axis at the top of the figure from 5´ to 3′, and genomic positions along chromosome 16 along with annotated genes are given above. Data are color-coded by phenotype and displayed as a square (for SNPs), a triangle (p-values), or closed circles (betas, CAFs, and sample size). Direction of the triangle represents the direction of the effect size.