Fig 10. The AMPK inhibitor CC prevents protective effects of the monounsaturated fatty acids oleate and palmitoleate.

Cells were pretreated with compound C (CC; 20 or 40μM) and then co-incubated with a combination of palmitate (PA) and oleate (Ole) or palmitoleate (PO). Fold change from control in a) viability with Ole, b) apoptosis with Ole, c) viability with PO and d) apoptosis with PO after co-treatment with palmitate (PA) and compound C (CC). Data are expressed as mean±SEM; n = 3–5 independent experiments; *p<0.05 vs control.