Skip to main content
. 2019 Dec 31;14(12):e0227197. doi: 10.1371/journal.pone.0227197

Table 2. Trends in thymic cancer age standardized rate by histologic types, sex, races in USCS, United States, 2001–2015.

Incidence Trend 1 Trend 2 2001–2015
2001 2015 Years APC 95% CI Years APC 95% CI AAPC
All histologic Types, both sexes, all races 0.23 0.30 2001–2006 4.9* 1.8–8.1 2006–2015 0.1 -1.0–1.2 1.8*
    Thymoma 0.16 0.19 2001–2008 2.9* 1.8–4.0 2008–2015 -0.9 -1.9–0.0 1.0*
    Thymic carcinoma 0.03 0.07 2001–2004 15.7 -2.1–36.7 2004–2015 2.6* 1.0–4.3 5.3*
    Thymic neuroendocrine tumor 0.01 0.01 2001–2015 -2.3 -4.7–0.2 -2.3
Sex
    Male 0.28 0.35 2001–2015 1.0* 0.1–2.0 1.0*
    Female 0.18 0.26 2001–2009 4.0* 1.9–6.2 2009–2015 -1.3 -3.9–1.5 1.7*
Race
    White 0.21 0.25 2001–2005 5.8* 0.8–11.1 2005–2015 -0.3 -1.4–0.8 1.4
    Black 0.33 0.50 2001–2015 2.0* 0.9–3.1 2.0*
    Asian/Pacific Islander 0.37 0.60 2001–2015 2.4* 0.2–4.6 2.4*
Male
    Thymoma 0.19 0.21 2001–2015 0.4 -0.5–1.3 0.4
    Thymic carcinoma 0.04 0.10 2001–2015 4.1* 2.5–5.8 4.1*
    Thymic neuroendocrine tumor 0.02 0.01 2001–2015 -2.9* -5.1 - -0.6 -2.9*
Female
    Thymoma 0.14 0.18 2001–2012 2.5* 1.5–3.6 2012–2015 -5.4 -11.9–1.6 0.8
    Thymic carcinoma 0.02 0.05 2001–2009 7.9* 3.0–13.0 2009–2015 -1.7 -6.9–3.7 3.7*
    Thymic neuroendocrine tumor - - - - - -

Abbreviation: CI, confidence interval; AAPC, average annual percent change over the most recent data years; APC, annual percent change

*The APC or AAPC is significantly different from zero (P < .05).