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. 2019 Dec 31;14(12):e0227004. doi: 10.1371/journal.pone.0227004

Fig 1.

Fig 1

A. Liver with very severe hyperemia, severe necrosis of individual/groups of hepatocytes and the presence of basophilic intra-nuclear inclusion bodies within hepatocytes. H&E, X400. B. Liver of SPF- chicken embryo inoculated with field liver homogenates showing multifocal necrosis of groups of hepatocytes and the presence of basophilic inclusions bodies (intra-nuclear) within hepatocytes. H&E, X40. C. Liver of SPF chicken embryo (higher magnification of Fig B)–foci of hepatocytes necrosis. Cellular debris and basophilic intra-nuclear inclusion bodies. H&E, X160.