Table 2.

Plasma Cytokine Analysis

Cytokine	Control (pg/mL)	HIV+ (pg/mL)	q-value
Innate
IL-1β	1.1 (0.7)	1.4 (1.7)	0.086
IL-6	0.9 (1.3)	1.6 (1.7)	0.105
TNFα	3.7 (2.7)	5.8 (4.4)	0.047*
IL-10	5.3 (3.9)	7.9 (12.0)	0.086
Th1
IL-12p70	0.9 (1.8)	1.5 (3.5)	0.038*
IFNγ	9.5 (7.1)	12.5 (18.4)	0.086
Th2
IL-4	1.8 (4.1)	10.0 (19.2)	0.069
IL-5	0.7 (1.8)	1.4 (1.8)	0.105
IL-13	1.9 (2.9)	1.7 (3.0)	0.430
Th17
IL-17A	2.5 (4.9)	2.2 (7.9)	0.313
IL-23	16.7 (33.6)	28.5 (133.9)	0.105
Other
IL-2	0.9 (0.9)	0.8(1.6)	0.705
IL-7	4.3 (3.2)	4.9 (8.2)	0.313
IL-21	0.5 (0.7)	0.7 (1.8)	0.105
GM-CSF	24.3 (47.0)	35.1 (33.6)	0.277
Chemokines
CXCL8 (IL-8)	2.9 (2.2)	3.6 (3.5)	0.311
CXCL11 (ITAC)	15.2 (27.2)	35.1 (41.6)	0.041*
CX3CL1 (Fractalkine)	35.7 (47.9)	71.9 (99.5)	0.038*
CCL3 (MIP-1α)	14.1 (7.4)	14.6 (9.2)	0.860
CCL4 (MIP-1β)	9.3 (6.1)	11.5 (5.0)	0.069
CCL20 (MIP-3α)	18.4 (17.8)	22.9 (24.7)	0.199

Cytokine concentration values represent medians (IQR).

q-values represent adjusted p-values based on FDR.

^*q <0.05