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. 2019 Dec 31;12:1. doi: 10.1186/s13148-019-0796-9

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© The Author(s). 2019

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Correlation between CpG − 628 methylation and pressure pain threshold. PPT is lower with higher methylation rates. a Healthy participants; linear regression shows no difference between genders (males R² = 0.057, females R² = 0.050). b Crohn patients; linear regression shows large differences between genders (males R² = 0.008, females R² = 0.250)