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. 2019 Dec 31;12:2. doi: 10.1186/s13148-019-0797-8

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Associations between circulating nucleosome levels and parameters of metabolic health. Circulating nucleosomes are assayed by ELISA in Kardiovize participants (n = 120) and expressed as absorbance. a Correlation matrix between circulating nucleosome levels and cardiometabolic parameters. The data are reported as the Spearman’s correlation coefficient and those with a p value < 0.05 are indicated in bold. b Comparison of circulating nucleosome levels across metabolic health categories and its components. The data represent the median and interquartile range and are compared using the Mann-Whitney U test; ***p < 0.001; *p < 0.05. c ROC curve showing the ability of serum circulating nucleosomes to discriminate patients with poor metabolic health. SBP systolic blood pressure, DBP diastolic blood pressure, TG triglycerides