Fig. 5.

BM-1197 exerts anti-tumor function by regulating the interaction between Bcl-2 family proteins. a. Cell lysates were subjected to co-IP using anti-Bcl-2 antibodies, followed by IB to detect the level of Bax, Bak, PUMA, Bim after treated with BM-1197. b. Cell lysates were subjected to co-IP using anti-Bcl-xl antibodies, followed by IB to detect the level of Bax, Bak, PUMA, Bim after treated with BM-1197. c. The input expression of Bcl-2 family protein after treated with BM-1197 in indicated time