Table 5.
The top 10 Gene Ontology enrichment functions
| Term | Count | P value | Genes |
| Negative regulation of transcription from the RNA polymerase II promoter | 9 | 0.001 | PHF19, SQSTM1, CPEB3, E2F7, ESR1, CBX2, SOX6, HMGA2, TWIST1 |
| Positive regulation of transcription regulatory region DNA binding | 3 | 0.002 | WNT3A, HMGA2, TWIST1 |
| Cytoplasm | 27 | 0.003 | CLSPN, CPEB3, TPM2, BDNF, RNF165, MAPT, STRIP2, HOXA10, FASN, PLCB1, CDC37L1, ARL2, IRAK1, SGK1, MAP2K1, KIF5A, DDX39B, PIM1, SOCS6, ESR1, SNAI2, WEE1, CDC25A, ADM, CA8, PSAT1, DUSP6 |
| Positive regulation of transcription, DNA-templated | 6 | 0.009 | RET, MAP2K1, FOXK1, MYRF, ESR1, PLCB1 |
| Osteoblast differentiation | 4 | 0.010 | WNT3A, FASN, SNAI2, TWIST1 |
| Neuron projection morphogenesis | 3 | 0.011 | BDNF, SGK1, WEE1 |
| Transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific | 5 | 0.019 | PLAG1, HOXA10, ESR1, HMGA2, MYBL2 |
| Negative regulation of sequence-specific DNA binding transcription factor activity | 3 | 0.021 | PIM1, ESR1, TWIST1 |
| Neuron projection | 4 | 0.027 | CPEB3, KIF5A, MAPT, SLC6A4 |
PHF19: PHD finger protein 19; SQSTM1: Sequestosome 1; CPEB3: Cytoplasmic polyadenylation element binding protein 3; E2F7: E2F transcription factor 7; ESR1: Estrogen receptor 1; CBX2: Chromobox 2; SOX6: SRY-box transcription factor 6; HMGA2: High mobility group AT-hook 2; TWIST1: Twist family bHLH transcription factor 1; WNT3A: Wnt family member 3A; CLSPN: Claspin; TPM2: Tropomyosin 2; BDNF: Brain derived neurotrophic factor; RNF165: Ring finger protein 165; MAPT: Microtubule associated protein tau; STRIP2: Striatin interacting protein 2; HOXA10: Homeobox A10; FASN: Fatty acid synthase; PLCB1: Phospholipase C beta 1; CDC37L1: Cell division cycle 37 like 1; ARL2: ADP ribosylation factor like GTPase 2; IRAK1: Interleukin 1 receptor associated kinase 1; SGK1: Serum/glucocorticoid regulated kinase 1; MAP2K1: Mitogen-activated protein kinase kinase 1; KIF5A: Kinesin family member 5A; DDX39B: DExD-box helicase 39B; PIM1: Pim-1 proto-oncogene, serine/threonine kinase; SOCS6: Suppressor of cytokine signaling 6; SNAI2: Snail family transcriptional repressor 2; WEE1: WEE1 G2 checkpoint kinase; CDC25A: Cell division cycle 25A; ADM: Adrenomedullin; CA8: Carbonic anhydrase 8; PSAT1: Phosphoserine aminotransferase 1; DUSP6: Dual specificity phosphatase 6; RET: Ret proto-oncogene; FOXK1: Forkhead box K1; MYRF: Myelin regulatory factor; PLAG1: PLAG1 zinc finger; MYBL2: MYB proto-oncogene like 2; SLC6A4: Solute carrier family 6 member 4.