Table 3. Adjusted OR (95% CI) of HRD and PRD by sex and history of depression status for participants from the CLSA Comprehensive Cohort at baseline.

	HRD		PRD
	OR	95% CI	OR	95% CI
Female (n = 11,293)
Group 2 (n = 1179)	1.13	0.89–1.44	1.07	0.93–1.24
Group 3 (n = 1560)	1.47	1.19–1.82	1.22	1.08–1.38
Group 4 (n = 780)	1.27	0.95–1.69	1.12	0.94–1.33
Male (n = 11,481)
Group 2 (n = 902)	1.11	0.90–1.37	1.04	0.89–1.22
Group 3 (n = 909)	1.26	1.03–1.55	1.18	1.01–1.37
Group 4 (n = 405)	1.39	1.05–1.84	1.28	1.03–1.58

Adjusted covariates include age, ethnicity, body mass index, marital status, education, income, immigrant, alcohol, smoker, physical activity, number of close of friend, and comorbidities. CI: confidence interval; CLSA: Canadian Longitudinal Study on Aging; HRD: heart related disorders; OR: odds ratio; PRD: peripheral/vascular related disorders. Group 1(reference): CES-D10 score < 10 and negative clinical depression history; Group 2: CES-D10 score ≥ 10 and negative clinical depression history; Group 3: CES-D10 score < 10 and positive clinical depression history; Group 4: CES-D10 score ≥ 10 and positive clinical depression history.