Table 4. Adjusted OR (95% CI) of HRD and PRD by age groups and history of depression status for participants from the CLSA Comprehensive Cohort.

	HRD		PRD
	OR	95% CI	OR	95% CI
Age 44–55 yrs (n = 6163)
Group 2 (n = 572)	1.10	0.78–1.55	1.00	0.84–1.19
Group 3 (n = 705)	1.79	1.34–2.38	1.23	1.05–1.43
Group 4 (n = 358)	1.04	0.68–1.60	1.18	0.95–1.46
Age 55–65 yrs (n = 7725)
Group 2 (n = 681)	1.21	0.91–1.60	1.25	1.04–1.51
Group 3 (n = 984)	1.15	0.89–1.48	1.11	0.95–1.30
Group 4 (n = 471)	1.64	1.21–2.23	1.14	0.91–1.43
Age 65–75 yrs (n = 5414)
Group 2 (n = 430)	1.12	0.81–1.54	0.95	0.74–1.22
Group 3 (n = 567)	1.19	0.90–1.58	1.20	0.96–1.49
Group 4 (n = 260)	1.08	0.71–1.64	1.08	0.77–1.51
Age over 75 yrs (n = 3472)
Group 2 (n = 398)	1.01	0.74–1.39	0.94	0.71–1.25
Group 3 (n = 213)	1.37	0.93–2.02	1.14	0.78–1.66
Group 4 (n = 96)	0.87	0.47–1.61	0.94	0.54–1.66

Adjusted covariates include age, sex, ethnicity, body mass index, marital status, education, income, immigrant, alcohol, smoker, physical activity, number of close of friend, and comorbidities. Group 1 (reference): CES-D10 score < 10 and negative clinical depression history; Group 2: CES-D10 score ≥ 10 and negative clinical depression history; Group 3: CES-D10 score < 10 and positive clinical depression history; Group 4: CES-D10 score ≥ 10 and positive clinical depression history. CI: confidence interval; CLSA: Canadian Longitudinal Study on Aging; HRD: heart related disorders; OR: odds ratio; PRD: peripheral/vascular related disorders.