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Effects of c-Myc knockdown on the growth of ADIR (58R3 and 58R4) cells to EGFRi. (A) Western blots showing reduced expression of Axl, EphA2, and ASS1 in two ADIR cells; (B) and (C) effects of c-Myc knockdown on cell proliferation of A2058 and ADIR treated with lapatinib and gefitinib, respectively; (D) and (E) increases of cell killing effects by JQ1 in combination therapy with ADI on 58R3 and 58R4, respectively.
