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. 2019 Dec 28;6(1):e02897. doi: 10.1016/j.heliyon.2019.e02897

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© 2019 The Author(s)

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Fig. 4 — Expression of SYP, PSD-95, MAP-2 and count of MVD in hippocampus among different groups (400×). Three rats' hippocampal specimens of perfusion sampling from each group were used for the analysis of immunohistochemistry and MVD. The upper images selected from the representative images of Sham operated Group, Model Group and MDP Group and showed the expressions of different synapse related key proteins and CD43-labeled microvessel density. Histogram in bottom left indicates the average optical density of SYP, PSD-95, MAP-2 in different groups; Histogram in bottom right indicates the mean number of MVD in different group. *: compared to the Model Group, P < 0.05; **: compared to the Model Group, P < 0.01; #: compared to the Sham operated Group, P < 0.05; ##: compared to the Sham operated Group, P < 0.01.