Table 3.
Associations of Interleukin 5 With Cardiovascular Risk Factors and T Cell Subsets
| Plasma IL-5 | p Value | PBMC IL-5 Release |
p Value | |
|---|---|---|---|---|
| Risk factors | ||||
| Age | −0.07 | ns | −0.11 | 0.006 |
| BMI | 0.03 | ns | 0.01 | ns |
| f-glucose | 0.00 | ns | 0.05 | ns |
| LDL | 0.00 | ns | 0.04 | ns |
| HDL | −0.05 | ns | −0.07 | ns |
| Triglycerides | −0.05 | ns | 0.04 | ns |
| hsCRP | 0.10 | 0.015 | 0.04 | ns |
| T cell subtypes | ||||
| CD4+ T cells | −0.07 | ns | 0.13 | 0.001 |
| Th1 T cells | −0.02 | ns | 0.13 | 0.001 |
| Th2 T cells | 0.04 | ns | 0.05 | ns |
| Regulatory T cells | −0.03 | ns | −0.03 | ns |
| CD8+ T cells | −0.13 | 0.001 | 0.13 | 0.001 |
| Oxidized LDL IgM | ||||
| MDA-p45 | 0.06 | ns | 0.09 | 0.036 |
| MDA-p210 | 0.01 | ns | −0.04 | ns |
Correlations are shown as Spearman rank correlation coefficients. The values for T cell subsets used in the analyses are the total numbers of each subset per milliliter of blood.
PBMC = peripheral blood mononuclear cell; other abbreviations as in Table 1.