Figure 8.
Impact of chronic GLP-1R antagonism of food intake and energy expenditure at the end of the weight gain protocol. A) Cumulative food intake was recorded over a 72-h period following an overnight fast in the control and GLP-1R Ab groups at the end of the study. B) Oxygen consumption, C) respiratory exchange ratio, and D) activity levels were measured in the control and GLP-1R Ab groups at the end of the study (n = 6/group). Values are mean ± SEM, *p < 0.05 vs IgG control. Statistical tests used: two-way ANOVA with a Bonferroni post-hoc test.