Table 2.
Degradation behavior of BMSs in vivo.
| Material | Animal model | Degradation in vivo | Ref. |
|---|---|---|---|
| Mg/PTMC coating | Subcutaneous of rats (52 W) | The homogeneous surface erosion of the PTMC coating from exterior to interior (surface-eroding behavior) and its charge neutral degradation products contribute to its excellent protective performance. | [67] |
| JDBM/MgF2 coating | abdominal aorta of rabbits (28 D) | Stents show excellent tissue compatibility of the well re-endothelialized stent with no sign of thrombogenesis and restenosis in the stent-supported vessel. | [68] |
| JDBM | common carotid artery of rabbits (20 M) | After 4 months implantation, stent has mostly degraded. | [66,69,70] |
| abdominal aorta of rabbits (16 W) | Stents well apposed to the vessel wall, with no sign of early recoil or fracture | ||
| WE43 | |||
| AZ31 | |||
| Common bile duct of rabbits (6 M) | About 60% volume loss after 3-month-implantation andno residue found afer 6-month-implantation. | [71] | |
| AZ31/silicone membrane | Oesophagus of rabbits | It provide good support for at least 2 weeks. | [72] |
| AZ91 | Coronary artery and femoral artery of dogs (28 D) | Stents were completely disappeared at 7 days after implantation. | [63] |
| Mg–6Zn | Rabbits | The in vivo corrosion rate of Mg–6Zn was ~0.107 mm year−1, which was much lower than that calculated in vitro. | [73] |