Table 2.
Characteristics of the population according to the indication of statin therapy recommended by the 2018 ACC/AHA and the 2016 ESC/EAS guidelines.
| 2018 ACC/AHA guidelines |
|||
|---|---|---|---|
| With statin-indication (n = 536) | Without statin-indication (n = 356) | p | |
| Continuous variables, mean (SD) | |||
| Age, years | 63.7 (11.6) | 54.3 (12.7) | <0.001 |
| Systolic blood pressure, mmHg | 131.4 (16.2) | 121.7 (13.7) | <0.001 |
| Diastolic blood pressure, mmHg | 79.8 (9.7) | 75.0 (9.1) | <0.001 |
| Body mass index, kg/m2 | 28.9 (6.2) | 27.1 (5.6) | 0.002 |
| Total cholesterol, mg/dL | 202.1 (44.1) | 192.7 (38.4) | 0.001 |
| LDL-C, mg/dL | 128.1 (35.9) | 117.3 (30.6) | <0.001 |
| HDL-C, mg/dL | 49.8 (13.8) | 54.1 (15.1) | <0.001 |
| Triglycerides, mg/dL | 125.7 (67.9) | 110.4 (73.4) | 0.002 |
| Non HDL-C, mg/dL | 152.4 (42.1) | 138.7 (36.3) | <0.001 |
| Blood glucose, mg/dL | 103.9 (29.4) | 96.2 (18.2) | <0.001 |
| Creatinine, mg/dL | 0.91 (0.26) | 0.88 (0.26) | 0.362 |
| Categorical variables (%) | |||
| Male gender | 57.5 | 27.5 | <0.001 |
| Hypertension | 66.9 | 35.1 | <0.001 |
| Smoking | 29.5 | 17.7 | <0.001 |
| Diabetes | 14.9 | 12.4 | 0.278 |
| Obesity | 37.4 | 21.4 | <0.001 |
| Psoriatic arthritis | 8.6 | 4.5 | 0.019 |
| 2016 ESC/EAS guidelines |
|||
|---|---|---|---|
| With statin-indication (n = 536) | Without statin-indication (n = 356) | p | |
| Continuous variables, mean (SD) | |||
| Age, years | 67.4 (12.7) | 47.9 (14.7) | <0.001 |
| Systolic blood pressure, mmHg | 130.7 (16.3) | 122.5 (13.9) | <0.001 |
| Diastolic blood pressure, mmHg | 78.7 (9.6) | 76.6 (9.7) | 0.002 |
| Body mass index, kg/m2 | 28.6 (6.1) | 27.5 (5.8) | 0.074 |
| Total cholesterol, mg/dL | 203.2 (42.6) | 190.5 (40.2) | 0.001 |
| LDL-C, mg/dL | 129.4 (34.3) | 115.5 (32.4) | <0.001 |
| HDL-C, mg/dL | 51.5 (14.9) | 51.3 (13.9) | 0.865 |
| Triglycerides, mg/dL | 124.2 (70.8) | 112.2 (69.5) | 0.014 |
| Non HDL-C, mg/dL | 151.7 (40.7) | 139.2 (38.8) | <0.001 |
| Blood glucose, mg/dL | 105.4 (30.6) | 93.5 (12.2) | <0.001 |
| Creatinine, mg/dL | 0.91 (0.27) | 0.87 (0.64) | 0.341 |
| Categorical variables (%) | |||
| Male gender | 50.6 | 37.4 | <0.001 |
| Hypertension | 66.2 | 35.1 | <0.001 |
| Smoking | 26.7 | 21.6 | 0.08 |
| Diabetes | 21.9 | 1.4 | <0.001 |
| Obesity | 34.3 | 25.4 | <0.001 |
| Psoriasic arthritis | 7.9 | 5.4 | 0.196 |