Table 1.

Reports of Hz/Hc cases described in the literature with dermatological evaluation.1, 3, 4

	Previous reports								Current report
Age at diagnosis	18	18	9	14	35	21	10	5	20
Sex	M	M	F	M	F	M	F	M	F
Growth	Reduced	Reduced	Reduced	Reduced	Normal	Normal	Reduced	Reduced	Reduced
Hepatosplenomegaly	–	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes
Skin lesions	PG	Vasc	No	No	Vasc, eczema	Vasc, ulcers	PG	Eyelid lesions	PG
Rheumatologic changes	–	Arthritis	Arthritis	Arthritis	Arthritis, uveitis	Arthritis	Arthritis	Arthritis	Arthritis
CRP (<10 mg/L)	–	41–143	100–200	22	17	45–146	60	108	35
Hemoglobin (g/L)	–	8	9	10.9	12.5	8	5.5	7.6	7.3
Zinc (10–18 μm/L)	120–197	180–200	82–96	160–200	175	77	183	152	138
Calprotectin (<0.001 g/L)	–	6.5	1.4–2.55	9	6.1	1.5	12.5	2.3	0.6

PG, pyoderma gangrenosum; Vasc, vasculitis; CRP, C-reactive protein.