. Author manuscript; available in PMC: 2020 Jan 2.

Published in final edited form as: Can J Neurol Sci. 2013 May;40(3):299–306. doi: 10.1017/s0317167100014232

Table:

Comparison of different subtypes of Parkinson’s disease

	Parkinson’s disease Clinical subtype
Clinical features	PD_T	PD_AR
Progression of motor symptoms	Slower/not worsening	Faster
Motor Fluctuations (on and off)/Freezing gait	Less	More
Inheritance	Higher prevalence of Essential Tremor	Higher familial incidence of other cases of PD
PET Scan	Does not correlate with nigrostriatal dopaminergic deficit	Correlates with nigrostriatal dopaminergic deficiency
SPECT
Pathology	Less neuronal loss in locus coeruleus, medial and lateral parts of SN	Higher neuronal losses in locus coeruleus, medial and lateral parts of SN

DLPFC= dorsolateral prefrontal cortex; PET= positron emission topography; SPECT= single-photon emission computed tomography; PD_T = tremor-dominant Parkinson’s patients; PD_AR= akinetic and rigid-dominant Parkinson’s patients; SN= substantia nigra