Figure 1.

Relationship between achieved systolic blood pressure (SBP) and cumulative risk of adverse outcomes. Meta-regression analyses were performed on the data from combining the intensive (colored in red) and standard (colored in blue) control groups. The regression fit (solid line) and 95% confidence interval (gray shaded area) for linear model and the regression fit (dash line) for nonlinear model are shown. The size of the circle represents the weight of each trial and is inversely proportional to the standard error of the effect estimate.