Table 1.

Clinical and laboratory comparison between patients with CVID and XLA

	CVID N = 749	XLA N = 320	P value*
Sex (male)	322 (43.0)	320 (100.0)	< 0.001
Age at last visit	39.50 [24.90, 50.30]	17.40 [8.43, 28.25]	< 0.001
Age of symptom onset	16.00 [6.00, 30.00]	1.00 [0.50, 2.15]	< 0.001
Age of diagnosis	29.90 [15.20, 42.70]	2.40 [1.00, 5.60]	< 0.001
CD4	664.00 [470.00, 927.00]	1576.50 [1120.00, 2426.75]	< 0.001
CD8	390.00 [246.50, 681.00]	795.84 [484.56, 1241.10]	< 0.001
CD19	176.00 [80.25, 309.25]	0.00 [0.00, 13.00]	< 0.001
Pre-diagnostic IgG	353 [186–514]	65 [25.5–325]	0.015
IgA	9.99 [6.64, 31.00]	6.66 [0.99, 8.14]	< 0.001
IgM	23.00 [10.99, 44.00]	10.00 [4.99, 22.00]	< 0.001

^*Chi-square test for categorical variables and Mann-Whitney test for continuous variables

Continuous variables were summarized as median [IQR] and categorical variables were summarized as counts (percentage)