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. 2019 Mar 29;24(2):348–358. doi: 10.1177/1087054719836159

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© The Author(s) 2019

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 2. — Subject disposition.

Note. ITT = intention-to-treat; PP = per-protocol.

aOne participant randomized to SPN-812 300 mg/day received 100 mg/day throughout the study; this participant is included in the 100 mg/day group in all safety analyses, but in the 300 mg/day group in all analyses based on the ITT population.