Table 4.
Target genes regulated indirectly by the two differentially expressed circRNAs through miRNAs
| circRNA | Sponged miRNAs | Gene Symbol | Gene Description |
|---|---|---|---|
| rno_circRNA_014900 |
rno-miR-193a-5p rno-miR-1224 |
Nova1 | neuro-oncological ventral antigen 1 |
|
rno-miR-193a-5p rno-miR-6332 |
Clasp1 | cytoplasmic linker associated protein 1 | |
|
miR-193a-5p rno-miR-466b-5p |
Rgs4, Mixl1 | regulator of G-protein signaling 4; Mix paired-like homeobox 1 | |
|
rno-miR-466b-5p rno-miR-6332 |
Usp37, RGD1566029, Zfp91, Zmiz1, Pbx1 | ubiquitin specific peptidase 37; similar to mKIAA1644 protein; zinc finger protein 91; zinc finger, MIZ-type containing 1; pre-B-cell leukemia homeobox 1 | |
|
rno-miR-466b-5p rno-miR-1224 |
Calcoco1 | calcium binding and coiled coil domain 1 | |
|
rno-miR-466b-5p rno-miR-6321 |
Brwd3, Nfat5, Cnot7, Camta1 | bromodomain and WD repeat domain containing 3; nuclear factor of activated T-cells 5, tonicity-responsive; CCR4-NOT transcription complex, subunit 7; calmodulin binding transcription activator 1 | |
|
rno-miR-6332 rno-miR-1224 |
Prpf4b, Hgs, Gtdc1, Dgkk | pre-mRNA processing factor 4B;hepatocyte growth factor-regulated tyrosine kinase substrate; glycosyltransferase-like domain containing 1;diacylglycerol kinase kappa | |
|
rno-miR-6332 rno-miR-6321 |
RGD1562037, Usp24,Ssbp2 | similar to OTTHUMP00000046255; ubiquitin specific peptidase 24; single-stranded DNA binding protein 2 | |
|
rno-miR-6332 rno-miR-6321 rno-miR-466b-5p |
Ssbp2, RGD1562037 | singe-stranded DNA binding protein 2; similar to OTTHUMP00000046255 | |
|
rno-miR-6332 rno-miR-466b-5p rno-miR-1224 |
Zfp91 | zinc finger protein 91 | |
| rno_circRNA_005442 |
rno-miR-107-5p rno-miR-323-5p |
Eps8,Rhot1 | epidermal growth factor receptor pathway substrate 8, ras homolog gene family, member T1 |
|
rno-miR-107-5p rno-miR-344b-5p |
Hn1 | hematological and neurological expressed 1 | |
|
rno-miR-107-5p rno-miR-135b-5p |
Ptk2,Tiam1 | protein tyrosine kinase 2;T-cell lymphoma invasion and metastasis 1 | |
|
rno-miR-107-5p rno-miR-135a(b)-5p |
Slc8a1,Man2a1,Tnpo1,Rgl1 | solute carrier family 8 (sodium/calcium exchanger), member 1; mannosidase, alpha, class 2A, member 1;transportin 1; ral guanine nucleotide dissociation stimulator,-like 1 | |
|
rno-miR-323-5p rno-miR-344b-5p |
Tomm6 | translocase of outer mitochondrial membrane 6 homolog (yeast) | |
|
rno-miR-323-5p miR-135a(b)-5p |
Shisa7 | shisa family member 7 | |
|
rno-miR-344b-5p miR-135a(b)-5p |
Arel1 | apoptosis resistant E3 ubiquitin protein ligase 1 | |
|
rno-miR-323-5p rno-miR-107-5p rno-miR-135a(b)-5p |
Rhot1 | ras homolog gene family, member T1 |