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. 2020 Jan 2;20:1. doi: 10.1186/s12888-019-2374-2

Table 5.

The signaling pathways that may be regulated by targeted genes of the differentially expressed rno_circRNA_014900(p < 0.05)

PathwayID Definition Fisher-Pvalue Enrichment_Score
rno04510 Focal adhesion - Rattus norvegicus (rat) 4.05765E-06 5.391726
rno05205 Proteoglycans in cancer - Rattus norvegicus (rat) 0.000263739 3.578826
rno05200 Pathways in cancer - Rattus norvegicus (rat) 0.000839484 3.075988
rno04216 Ferroptosis - Rattus norvegicus (rat) 0.000947662 3.023347
rno04015 Rap1 signaling pathway - Rattus norvegicus (rat) 0.001242467 2.905715
rno00564 Glycerophospholipid metabolism - Rattus norvegicus (rat) 0.001767738 2.752582
rno04310 Wnt signaling pathway - Rattus norvegicus (rat) 0.002533546 2.596271
rno05165 Human papillomavirus infection - Rattus norvegicus (rat) 0.003213976 2.492957
rno04140 Autophagy - animal - Rattus norvegicus (rat) 0.00464105 2.333384
rno05222 Small cell lung cancer - Rattus norvegicus (rat) 0.005031787 2.298278
rno04070 Phosphatidylinositol signaling system - Rattus norvegicus (rat) 0.006461245 2.189684
rno00561 Glycerolipid metabolism - Rattus norvegicus (rat) 0.00791785 2.101393
rno04213 Longevity regulating pathway - multiple species - Rattus norvegicus (rat) 0.00791785 2.101393
rno04730 Long-term depression - Rattus norvegicus (rat) 0.00791785 2.101393
rno04151 PI3K-Akt signaling pathway - Rattus norvegicus (rat) 0.00874211 2.058384
rno04512 ECM-receptor interaction - Rattus norvegicus (rat) 0.009516369 2.021529
rno04137 Mitophagy - animal - Rattus norvegicus (rat) 0.009920558 2.003464
rno04728 Dopaminergic synapse - Rattus norvegicus (rat) 0.01248382 1.903653
rno04211 Longevity regulating pathway - Rattus norvegicus (rat) 0.01286284 1.890663
rno04136 Autophagy - other - Rattus norvegicus (rat) 0.01346501 1.870793
rno04150 mTOR signaling pathway - Rattus norvegicus (rat) 0.01358861 1.866825
rno04115 p53 signaling pathway - Rattus norvegicus (rat) 0.01402018 1.853246
rno04215 Apoptosis - multiple species - Rattus norvegicus (rat) 0.01492946 1.825956
rno05214 Glioma - Rattus norvegicus (rat) 0.01496318 1.824976
rno04270 Vascular smooth muscle contraction - Rattus norvegicus (rat) 0.02428063 1.61474
rno01521 EGFR tyrosine kinase inhibitor resistance - Rattus norvegicus (rat) 0.02549639 1.593521
rno05219 Bladder cancer - Rattus norvegicus (rat) 0.02580699 1.588263
rno05224 Breast cancer - Rattus norvegicus (rat) 0.02850884 1.54502
rno05166 HTLV-I infection - Rattus norvegicus (rat) 0.02925304 1.533829
rno04066 HIF-1 signaling pathway - Rattus norvegicus (rat) 0.03188594 1.496401
rno04068 FoxO signaling pathway - Rattus norvegicus (rat) 0.03490339 1.457132
rno04144 Endocytosis - Rattus norvegicus (rat) 0.03599259 1.443787
rno04720 Long-term potentiation - Rattus norvegicus (rat) 0.03856442 1.413813
rno04978 Mineral absorption - Rattus norvegicus (rat) 0.04045532 1.393024
rno04725 Cholinergic synapse - Rattus norvegicus (rat) 0.04272807 1.369287
rno05030 Cocaine addiction - Rattus norvegicus (rat) 0.04327309 1.363782
rno04010 MAPK signaling pathway - Rattus norvegicus (rat) 0.04346333 1.361877
rno04120 Ubiquitin mediated proteolysis - Rattus norvegicus (rat) 0.04667443 1.330921
rno00062 Fatty acid elongation - Rattus norvegicus (rat) 0.04768946 1.321578
rno05211 Renal cell carcinoma - Rattus norvegicus (rat) 0.04775832 1.320951
rno01522 Endocrine resistance - Rattus norvegicus (rat) 0.04798442 1.3189