TABLE 2.

Cox Regression for Overall Survival of Thalamic Glioblastomas at Memorial Sloan Kettering Cancer Center

				Univariate			Multivariate
Variable	Level	n	%	HR	95% CI	P-value	HR	95% CI	P-value
Location	Right	29	54	ref	–	–
(bilateral excluded due to small N	Left	25	46	1.17	0.66-2.10	.59
Surgery	Biopsy	47	82	ref	–	–
	Craniotomy	10	18	0.94	0.47-1.88	.86
Hydro	No	30	53	ref	–	–
	Yes	27	47	0.98	0.56-1.73	.94
Headache	No	30	53	ref	–	–
	Yes	27	47	0.69	0.39-1.23	.21
N/V	No	44	77	ref	–	–
	Yes	13	23	1.18	0.60-2.33	.63
Motor symptoms	No	22	39	ref	–	–
	Yes	35	61	1.63	0.89-2.98	.12
Sensory symptoms	No	37	65	ref	–	–
	Yes	20	35	1.10	0.62-1.95	.73
Language symptoms	No	45	79	ref	–	–	ref	–	–
	Yes	12	21	2.36	1.17-4.73	.02	1.61	0.76-3.41	.21
Visual symptoms	No	43	75	ref	–	–
	Yes	14	25	0.79	0.42-1.50	.47
Confusion	No	29	51	ref	–	–
	Yes	28	49	1.03	0.59-1.80	.93
Memory loss	No	33	58	ref	–	–
	Yes	24	42	1.01	0.58-1.77	.97
VPS	No	37	65	ref	–	–	ref	–	–
	Yes	20	35	0.43	0.23-0.80	.008	0.58	0.29-1.13	.11
Midbrain	No	39	68	ref	–	–
	Yes	18	32	0.86	0.48-1.57	.63
Gender	Female	26	46	ref	–	–
	Male	31	54	1.18	0.67-2.08	.58
Volumetrics	–	–	–	1.01	0.99-1.03	.22
Age at surgery–continuous	–	–	–	1.02	1.002-1.042	.03	1.02	0.996-1.04	.11
Preop KPS–continuous	–	–	–	0.96	0.94-0.99	.0009	0.97	0.95-0.99	.01