Table 2.
Parameter | PAH (n = 28) | CTEPH (n = 17) |
---|---|---|
Haemodynamic parameters, median, IQR | ||
mPAP (mmHg) | 44.5 (35.5-52.5) | 36.0 (29.0-41.0) |
PVR (Wood units) | 469 (354.0-652.7) | 264 (218.3-419.6) |
CI (L/min/m2) | 3.3 (2.96-4.05) | 3.52 (3.13-4.07) |
mRAP (mmHg) | 6.4 (4.5-7.0) | 5.0 (4.0-8.0) |
SatO2mix (%) | 72.3 (66.076.8) | 75.8 (70.8-79.4) |
PAH and CTEPH specific treatment | ||
Monotherapy (n, %) | ||
Riociguat | 1 (4) | 16 (94) |
Sildenafil | 4 (14) | 0 (0) |
Bosentan | 4 (14) | 0 (0) |
Macicentan | 1 (4) | 0 (0) |
Combined therapy (n, %) | ||
Sildenafil+treprostinil sc | 6 (21) | 0 (0) |
Sildenafil+macicentan | 3 (11) | 0 (0) |
Sildenafil+iloprost | 2 (7) | 0 (0) |
Sildenafil+bosentan | 1 (4) | 0 (0) |
Sildenafil+iloprost+bosentan | 4 (14) | 0 (0) |
Sildenafil+oral treprostinil+macicentan | 1 (4) | 0 (0) |
Sildenafil+oral treprostinil | 1 (4) | |
Baloon pulmonary angioplasty | 0 (0) | 15 (88) |
mPAP: mean pulmonary artery pressure; PVR: pulmonary vascular resistance; CI: cardiac index; mRAP: mean right atrium pressure; SatO2mix: mixed venous oxygen saturation; PAH: pulmonary arterial hypertension; CTEPH: chronic thromboembolic pulmonary hypertension.