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. 2019 Dec 19;2019:8061901. doi: 10.1155/2019/8061901

Figure 1.

Figure 1

The miR-200 family increases in lesional vs. nonlesional skin of psoriatic patients. Total RNA was extracted from nonlesional skin (NLS) and lesional skin (LS) of 6 psoriatic patients and from 6 healthy control skin biopsies (HS). The RNA was assayed for miR-200c family expression by qRT-PCR. The entire miR-200 family was upregulated in LS compared to NLS. (a) miR-200c was upregulated in LS compared to HS (Mann-Whitney test; ∗∗P < 0.01) and in LS vs. NLS (Wilcoxon rank test; ∗P < 0.05). (b) miR-200a was upregulated in LS vs. NLS (P = 0.06). (c) miR-200b was upregulated in LS compared to NLS (Wilcoxon rank test; ∗P < 0.05). (d) miR-141 was upregulated in LS with respect to NLS (Wilcoxon rank test; ∗P < 0.05). (e) miR-429 was downregulated in NLS compared to HS (Mann-Whitney test; ∗∗P < 0.01) and upregulated in LS compared to NLS (Wilcoxon rank test; ∗P < 0.05).