Table 1:
Baseline Patient and Operative Characteristics
| Katz Atheroma Grade | |||
|---|---|---|---|
| Mild (I or II) (N=220) | Moderate or Severe (III-V) (N=106) | p-value | |
| Age | 73.4±6.7 | 75.1±6.2 | 0.03 |
| BMI | 29.5±5.9 | 30.2±6.1 | 0.28 |
| Male | 135(61.4) | 67(63.2) | 0.75 |
| White Race | 207(94.1) | 96(90.6) | 0.35a |
| Medical History | |||
| Severe Carotid Artery Disease(>80% stenosis) | 7(3.2) | 2(1.9) | 0.72 |
| Peripheral Vascular Disease | 18(8.2) | 26(24.5) | <0.001 |
| Hypertension | 179(81.4) | 89(84.0) | 0.57 |
| Diabetes | 62(28.2) | 39(36.8) | 0.12 |
| History of AF | 22(10.0) | 16(15.1) | 0.18 |
| History of Stroke or TIA | 19(8.6) | 12(11.3) | 0.44 |
| Chronic Renal Insufficiency | 26 (11.8) | 16 (15.1) | 0.41 |
| Creatinine (mg/dl) | 1.0 (0.8,1.1) | 1.0 (0.8,1.2) | 0.87 |
| White Matter Lesion Volume(mm3) | 5433 (2679,8870) | 4782 (2258,10242) | 0.66 |
| White Matter Lesion Volume/Intracranial Volume | 0.005 (0.002,0.008) | 0.004 (0.002,0.009) | 0.67 |
| Operative Characteristics | |||
| Use of Embolic Protection Filter Deviceb | 138(62.7) | 73(68.9) | 0.28 |
| Largest particle size(mm)c | 0.7 (0.3,1.2) | 0.8 (0.4,1.1) | 0.76 |
| Presence of debrisc | 116(87.9) | 63(87.5) | 0.94 |
| Concomitant CABG | 85(38.6) | 47(44.3) | 0.33 |
| Operation Time(min) | 311.8±85.4 | 336.3±100.9 | 0.03 |
| CPB Time(min) | 104.2±41 | 108.5±42.6 | 0.39 |
Results are reported as n(%), mean±SD, or median (IQR).
a
P-value for race is computed excluding those who are unknown
b
In this patient sample, 4 patients who were randomized to a device received the standard cannula. The numbers provided are based on the device used rather than randomization assignment.
c
Among patients who received an embolic protection filter device.
AF: atrial fibrillation; BMI: body mass index; CABG: coronary artery bypass graft; CPB: cardiopulmonary bypass; TIA: transient ischemic attack