(a) 3,5-Bis(trifluoromethyl)phenyl boronic acid, Pd(dppf)2Cl2, Na2CO3, toluene, EtOH, H2O, 100 °C, 2 hr; (b) di-tert-Butyl-(chloromethyl)phosphate, Cs2CO3, Nal, DMF, 60 °C, 16 hr; (c) Methylhydrazine 60%, EtOH, 80 °C, 1 hr; (d) TFA, DCM, room temp. 1 hr.