FIG. 4.

ARDS gene table and top pathways. Two hundred one genes identified through differential gene expression (mRNA sequencing, mRNA CHIP array, RNA microarray, proteomics, candidate gene sequencing, or GWAS) that mapped onto either the Reactome or Wikipathways databases for pathway analysis (5359 human pathways covered). The second, third and fourth columns reflect the number of citations for each gene (14). Four broad categories of enriched pathways (immunological signaling, ROS-related signaling, vascular signaling, and transcription factor-related pathways) and the number or genes represented in each (p < 0.01, five members minimum per pathway). GWAS, genome-wide association study; ROS, reactive oxygen species.