FIG. 5.

Heatmap of PBMC gene expression predicting ARDS susceptibility and ARDS mortality. (A) The 33 top genes identified in a molecular survival signature from PBMC mRNA in ARDS patients (n = 23) versus controls (n = 80, PMID:19222302). Nineteen genes are downregulated, and 14 are upregulated (Fold change >2 ± 4.41, p < 7.26e-23). (B) 22 genes in the ROS pathway were predictive of ARDS survival in ARDS patients. Five of these genes are upregulated, and 17 are downregulated (24). PBMC, peripheral blood mononuclear cell.